Instrumentation updates

2016 was a busy year with our move from UF and setting things up at UGA. We are finally getting where we want to be now.

Our first major instrument was the worm sorter

Then we got a new 600 MHz AVIII-HD Bruker NMR for metabolomics (with sample changer): wonderful instrument!

A month ago we upgraded our 800 MHz to the latest Bruker for metabolomics (with sample changer). We are still waiting for some specialized probes, especially a 1.5-mm cryo.

Last month we also ordered the final upgrade to our 900 MHz system for structural biology. Guess which company got that order?

New Grants!

The past few months have been quite productive. As the saying goes, “the harder I work, the luckier I get”!

New NIH RO1 (with Bill Brey, NHMFL): Development of a High-sensitivity 13C NMR Probe for Metabolomics

New Moore Foundation (with Mary Ann Moran, UGA): Assessing the movement of carbon currencies between marine microbes

New NSF (again with Mary Ann): Metabolic Currencies of the Ocean Carbon Cycle

NIH Admin supplement (with Ted Ross, UGA): Predictive modeling to identify biomarkers of disease severity in Zika virus infections

NIH RO1 (with Maureen Keller-Wood): Effects of Maternal Cortisol on Fetal and Neonatal Growth and Metabolism

Stay tuned for more that might be on the horizon!

Happy 2017!

We have added several people recently to the lab.

Max Colonna moved from a research scientist to a first year Biochemistry grad student. Max is co-mentored by Shaying Zhou (IOB and Biochemistry), so we also get to start an exciting new project with her lab!

Sicong Zhang joined the lab as a first year Biochemistry grad student. Sicong is very good with MATLAB, so she will be helping with several projects. Her main project will be to work on the new Phytoplankton project with Mary Ann Moran (UGA Marine Sciences).

Dr. Haris Panagos started as a postdoc near the end of 2016. Haris will be splitting his time between technical support in the NMR facility and working on the new phytoplankton project.

Welcome, yawl!!

Getting things going

The Edison lab officially starts in the CCRC at UGA Aug 14, but we have already been very busy laying the foundation of our new lab.

  • The first (of 3) new Bruker NMR consoles has been ordered and should be delivered in early fall. This will be set up perfectly for metabolomics and will allow us to take our existing Bruker protocols that were established at UF and get them going quickly.
  • We’ve ordered a new worm sorter (Union Biometrica Biosorter-Pro), which should be ready to go about the time we arrive in Athens. This will allow us to sort C. elegans by size and/or fluorescent properties, and we can accurately count worms into 96 well plates or other formats. I am very excited to start thinking of new approaches to metabolomics and automation with this machine readily available.
  • We are ordering some additional new equipment and computers to replace things that we had at UF, and it is nice to be able to update things. For example, everything will be as compatible as possible with 96 well formats, so that we have an efficient metabolomics workflow.
  • We’ve started using a new electronic lab notebook called labguru. I’ve wanted to have something like this for some time, and so far I’m very happy with it. We have a chemical and freezer inventory (thanks to Ramadan, my lab manager at UF). This links nicely into protocols that students and postdocs are making. We can keep conversations on specific topics going, and it seems much better than email to update conversations. We even have implemented a “paper of the week”, in which everyone puts up a post with a short description of a paper they like and why we should read it. The list of suggestions are now adding up to be a nice collection of important lab papers that we could use one day for journal clubs, etc. Now, I just need to keep up my weekly contributions!

This is a fun and exciting time for us, and it is allowing me to think of new experiments and projects that I haven’t considered in the past. Change can be very healthy in the right doses!

Students interested in the lab should contact me (aedison@uga.edu).